AtremoPlus: our Users report less pain! (part 2)

AtremoPlus Users report a diminution of chronic pain!

In our recent customer feedback survey (you can still take part in the survey by clicking here)! we questioned our clients about the evolution of their pain.  64% of participants reported an average 63% improvement in their pain!

Every human being deserves to live without pain, especially chronic pain that significantly reduces our daily life quality. Chronic pain is a permanent reminder that our organism does not function well and that we are suffering from a disease, for most of our clients, Parkinson’s disease.

So, the interesting question is, what mechanisms trigger pain in Parkinson’s? And, what active ingredients could explain why AtremoPlus users experience a fast and significant pain reduction?

To understand, we need to answer the question: what is precisely the Origin of pain?

Multiple pathways can trigger pain.
Oxidation and subsequent inflammation are considered to be some of the most evident physiological mechanisms that trigger pain. Once these two parameters get out of control in the body with aging and disease, the problem of pain becomes chronic with its devasting impact on our quality of life.  While these processes of oxidation and inflammation are complex and interconnected, they can contribute to pain through various mechanisms. Here are some of the main mechanisms:

1. Free Radical oxidative Damage: Oxidative stress, characterized by an excess of free radicals, can damage cells, including nerve cells, disrupting their normal functioning. This damage can result in neuropathic pain characterized by shooting or burning sensations.
2. Immune Response: Inflammation is the body’s natural response to injury or infection. When tissues become inflamed, immune cells release inflammatory molecules that can activate pain pathways in the nervous system that promote pain perception.
   Parkinson’s is known for being related to chronic nerve inflammation. Prolonged inflammation can lead to central sensitization, where the central nervous system becomes more sensitive to pain signals. This can result in chronic pain conditions.
   In some cases, inflammation may be triggered by autoimmune reactions, where the immune system mistakenly targets the body’s own tissues and triggers pain. Even if the origin of pain is multifactor, some scholars discuss the auto-immune component in Parkinson’s disease.
   Inflammation can also cause tissue swelling and compression of nerves, leading to pain.

It is incredible to learn what different kinds of pains can affect people with Parkinson’s. You can find our previous article, part 1 of pain reduction, by clicking here to learn more about the different types of pain in Parkinson’s disease. 

How do active ingredients in AtremoPlus work to promote pain reduction?

Even though the most important thing is that the results of pain reduction are reported by our customers, with the survey showing that many AtremoPlus users are observing a very significant reduction in their pain, it is interesting to understand how the active ingredients in AtremoPlus can contribute to impacting positively the reported pain reduction.
Nearly all active ingredients at trace levels of AtremoPlus, such as Flavonoids, Carotenoids, amino acids, some of the contained minerals, and Vitamins, are known to be highly effective in fighting oxidative stress and inflammation. The combined and complementary action could give already a very good explanation. Some minerals, such as magnesium, can also contribute to muscle relaxation, zinc is known for its anti-inflammatory effects, and Vitamin E is known as a powerful anti-oxidant, confirmed by the allegations allowed by the European Commission.
We have reasons to consider that this specific natural mix of all these oligo-elements can give a reasonable explanation as to why our customers report these significant pain reductions.

In addition to these anti-oxidative and anti-inflammatory mechanisms that fight the underlying causes directly, there are also some other causes that could explain why the standardized natural L-Dopa (levodopa) in AtremoPlus can explain certain of the good effects on pain reduction.  Here’s how L-Dopa is to pain management in the context of Parkinson’s disease:

1. Indirect Pain Relief: L-Dopa can indirectly contribute to pain relief in people with Parkinson’s disease by improving motor problems. Pain in Parkinson’s disease can be exacerbated by movement difficulties and muscle stiffness. It is known that off-periods can be correlated to pain. When L-Dopa and Carbio-Dopa components of AtremoPus improve these motor symptoms, it can lead to greater mobility and reduced discomfort, indirectly alleviating pain. Also, balance and posture are regularly improved with a positive impact on pain and fewer falls that can trigger additional acute pain.
   
   
2. Dyskinesias: It’s important to note that long-term use of L-Dopa can lead to motor fluctuations and dyskinesias (abnormal involuntary movements), which can themselves be uncomfortable or painful. Managing better these motor complications may also involve a pain reduction.

Indeed, our L-dopa of 100% plant origin is usually very well tolerated and acts in harmony with the numerous additional oligo-elements. The carbio-dopa effects of the polyphenols improve the use and prolonged bioavailability of the L-dopa,  allowing the L-dopa to cross the brain-blood barrier and be used in the brain.

The virtuous circle of less pain, better life quality, and better sleep quality

The mechanisms of action of the active ingredients contained in AtremoPlus make it easier to understand the link with the reduced pain that has been reported by a majority of our customers.

Less pain often means better sleep quality (see our previous series of newsletters on this subject by clicking on the links below).  All in all, we notice, that our customers enter rapidly into a virtuous circle and feel more alive and more present, many of them with reduced pain that allows them to better enjoy life.

We are glad to contribute to the well-being of our clients and wish you a lovely week ahead! 

Your Atremoplus Team